Briumvi^®

What is Briumvi^®?

Briumvi® (ublituximab-xiiy) is a monoclonal antibody therapy used to treat adults with relapsing forms of multiple sclerosis (MS). It belongs to a class of treatments known as anti-CD20 therapies, which work by targeting and reducing certain B cells—immune cells that play a central role in the body’s attack on the nervous system in MS. For individuals requiring B-cell–depleting therapy, Briumvi® provides an effective and efficient treatment option. It’s designed with a shorter infusion time, helping make the therapy process smoother and more convenient for patients and care teams alike.

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How does Briumvi^® work?

In multiple sclerosis (MS), the immune system mistakenly targets the myelin sheath — the protective layer surrounding nerve fibers in the brain and spinal cord. Once this layer is damaged, nerve signals can’t travel properly, leading to symptoms that affect coordination, movement, vision, speech, and even balance or bowel control.

Briumvi® focuses on a particular group of immune cells called B cells, which carry a marker called CD20. These cells are a key part of the inflammatory activity in MS. By binding to the CD20 marker, Briumvi® helps eliminate harmful B cells before they can cause additional nerve damage.

While it is not a cure for MS, Briumvi® helps calm the immune system, reducing disease activity and slowing progression over time.

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Why Patients Choose Rocky Mountain Infusion Center to Receive Their Briumvi^® Infusion:

Clinical Excellence and Neurological Expertise

Our infusion center is led by board-certified neurologists and supported by a team of BSN-prepared and Registered Nurses who specialize in infusion therapies for neurological conditions. We’re committed to providing a comfortable, professional, and compassionate treatment experience for every patient.

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Lower Costs and Financial Assistance

We take care of prior authorization and benefits verification, and assist with copay and foundation support programs. Our focus is on minimizing financial stress while ensuring you have full access to care.

A Cigna study found that patients treated at physician-owned infusion centers—like Rocky Mountain MS Clinic’s Infusion Center—often pay significantly less out of pocket and experience lower overall costs compared to hospital outpatient infusion centers.

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Established leader in MS & Neurological care

With 35+ years of experience in neurological care, Rocky Mountain MS Clinic has been a trusted destination for individuals living with MS and related disorders across the region. Our team’s long-standing expertise and patient-centered approach continue to make a difference in improving lives every day.

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How much does Briumvi^® cost?

The cost of Briumvi® varies based on factors like insurance coverage and individual benefits. At Rocky Mountain MS Clinic, we’re dedicated to keeping care accessible and affordable for every patient.

We collaborate with nearly all major insurance providers throughout the region — including Aetna, Anthem, Blue Cross Blue Shield, Cigna, Humana, UnitedHealthcare, and others — along with Medicaid and Medicare.

Our team takes care of prior authorizations, benefits verification, and paperwork for you. We’ll also walk you through copay assistance and foundation programs to help reduce out-of-pocket expenses and make treatment easier to manage financially.

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