Uplizna®
What is Uplizna®?
Uplizna® (inebilizumab-cdon) is a monoclonal antibody approved for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adults who are anti-AQP4 antibody positive. As an anti-CD19 therapy, Uplizna® targets and depletes B cells — immune cells involved in inflammation and nerve damage seen in NMOSD.
Uplizna® offers an important treatment option to help reduce the frequency of attacks, prevent long-term disability, and preserve neurological function, with the convenience of twice-yearly dosing after the initial infusions.
How much does Uplizna® cost?
Uplizna® cost varies depending on insurance coverage and provider. The team at Rocky Mountain MS Clinic is dedicated to helping patients access affordable, high-quality care.
We work with most major insurance providers across the Rocky Mountain region — including Aetna, Anthem, Blue Cross Blue Shield, Cigna, Humana, Select Health, Tricare, and others — as well as Medicaid and Medicare.
Our staff manages all prior authorizations and benefits verification and assists patients in applying for copay and foundation support programs to minimize out-of-pocket costs.
How does Uplizna® work?
In neuromyelitis optica spectrum disorder (NMOSD), the immune system mistakenly attacks the optic nerves and spinal cord, leading to symptoms like vision loss and paralysis.
B cells carrying the CD19 marker play a key role in producing harmful antibodies against aquaporin-4 (AQP4), which drive these attacks. Uplizna® binds to and eliminates CD19-positive B cells before they can trigger inflammation and nerve damage.
While not a cure for NMOSD, it helps calm immune activity, reduce the risk of relapses, and protect long-term function.
Why Patients Choose Rocky Mountain Infusion Center to Receive Their Uplizna® Infusion:
Clinical Excellence and Neurological Expertise
Our infusion center features a board-certified neurologist and a team of BSN-prepared and Multiple Sclerosis-certified Registered Nurses, all experienced in administering complex neurological infusions.
Lower Costs and Financial Assistance
We take care of insurance coordination and guide patients through copay and financial assistance programs.
A Cigna study shows that patients receiving infusions at physician-owned centers like Rocky Mountain MS Clinic’s Infusion Center often pay significantly less than at hospital-based centers.
Established leader in MS & Neurological care
With more than 35 years of experience, our clinic has been a trusted destination for patients throughout the Intermountain region seeking expert, compassionate neurological care.
The infusion clinic nurses are highly trained in Neurological conditions, personable, professional and careful. Having a doctor and team like this on your side of the fight against MS is invaluable.
They are constantly improving their in-house infusion center to ensure the comfort of their patients. The team there is professional and highly trained!
As someone who frequents their infusion center on a monthly basis, I can confidently say that it's top-notch. The staff at the infusion center are amazing, providing not only excellent medical care but also creating a comfortable and soothing environment for patients. Their dedication to patient comfort and well-being is evident in every aspect of the center.
Important Info
Immunoglobulin G4-related disease (IgG4-RD)
Neuromyelitis Optica Spectrum Disorder (NMOSD)
Immunoglobulin G4-related disease (IgG4-RD): Approved on April 3, 2025
Neuromyelitis Optica Spectrum Disorder (NMOSD): Approved on February 10, 2006
Viela Bio