^{Vyvgart® Infusions: What Is It & Where To Get It}

What is Vyvgart®?

Vyvgart® (efgartigimod) is an FDA-approved IV infusion therapy for adults with generalized myasthenia gravis (gMG) who are positive for anti-acetylcholine receptor (AChR) antibodies. In gMG, the immune system produces harmful IgG autoantibodies that interfere with nerve-to-muscle communication, leading to muscle weakness, fatigue, and difficulty performing everyday tasks such as walking, lifting, speaking, or swallowing.

Vyvgart® works by blocking the neonatal Fc receptor (FcRn), which is responsible for maintaining IgG levels in the blood. By reducing these damaging autoantibodies, Vyvgart® helps restore normal nerve-muscle communication, improving muscle strength, reducing fatigue, and enhancing daily functioning.

Delivered as an IV infusion at our specialized infusion center, Vyvgart® ensures controlled dosing, careful monitoring, and one-on-one support from trained nurses throughout treatment.

Vyvgart Infusion Frequency and Schedule:

• Initial treatment: Weekly infusions for four consecutive weeks
• Maintenance treatment: Subsequent cycles scheduled as recommended by your neurologist

Vyvgart IV Infusion Duration:

• Infusion duration: Approximately 1 hour per session
• Observation period: Patients are monitored during and after each infusion for any reactions
• Total appointment time: Generally 2–3 hours including preparation and post-infusion observation

How Does Vyvgart Work?

In generalized myasthenia gravis, IgG autoantibodies attack the acetylcholine receptors at the neuromuscular junction, preventing nerves from signaling muscles properly. This immune activity causes:

• Weakness in arms, legs, face, and neck
• Fatigue during routine activities
• Difficulty walking, lifting, speaking, or swallowing
• Breathing difficulties in severe cases

Vyvgart works through a targeted mechanism:

• Blocks FcRn: Prevents the receptor from maintaining harmful IgG autoantibodies.
• Reduces pathogenic IgG levels: Lowers the antibodies that interfere with nerve-muscle communication.
• Restores neuromuscular signaling: Improves muscle strength and endurance.
• Reduces symptoms and flare-ups: Helps patients maintain daily function and quality of life.

Many patients notice improvements in muscle strength and energy within the first treatment cycle, although individual responses may vary. While Vyvgart® is not a cure, it helps manage disease activity and supports long-term functional improvement.

Most patients tolerate Vyvgart® very well. You may experience mild or temporary side effects such as:

• Headache
• Fatigue
• Upper respiratory infections (stuffy or runny nose, sore throat)
• Infusion site reactions like redness, itching, or mild swelling
• These effects usually improve within a few hours to a few days. Some patients may not experience any side effects at all.

Your healthcare team closely monitors you during and after each infusion to ensure safety and promptly manage any side effects.

How Much Does Vyvgart® Cost?

The Vyvgart infusion cost depends on insurance coverage and provider. At Rocky Mountain MS Clinic, we're dedicated to improving access and affordability for all our patients seeking effective migraine prevention.

We work with most major insurance plans throughout Utah, including Aetna, Anthem, Blue Cross Blue Shield, Cigna, Humana, and UnitedHealthcare, along with Medicaid and Medicare. 

Our infusion staff provides comprehensive support to make treatment more accessible:

• Manages all prior authorizations and benefits verification
• Provides clear information about expected out-of-pocket costs
• Assists with copay assistance programs and foundation support
• Explores manufacturer patient assistance programs to reduce treatment costs

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Why Patients Choose Rocky Mountain MS Clinic's Infusion Center to Receive Their Vyvgart Infusion

Clinical Excellence and Neurological Expertise

Our infusion center is led by board-certified neurologists and supported by a team of BSN-prepared Registered Nurses who specialize in neurological infusion care. Our team has extensive experience treating patients with both episodic and chronic migraine.

Our approach to myasthenia gravis treatment includes:

• Thorough evaluation to determine if Vyvgart is appropriate for your generalized myasthenia gravis
• Careful monitoring during infusions for any allergic reactions
• Coordination with your overall migraine management plan
• Support in tracking your response to treatment over time

Beyond generalized myasthenia gravis, our comprehensive neurological expertise extends to multiple sclerosis, neuromuscular disorders, movement disorders, and other conditions. 

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Lower Costs and Financial Assistance

We help patients handle insurance paperwork and access copay and foundation assistance to make treatment more affordable.

A Cigna report recently found that infusions at physician-owned centers like Rocky Mountain MS Clinic's Infusion Center often result in lower overall costs than at hospital outpatient centers, making your quarterly Vyvgart treatments more economical.

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35+ Years of Trusted Neurological Care

For over 35 years, Rocky Mountain MS Clinic has served thousands of individuals across the region. Our decades of experience treating complex neurological and autoimmune conditions means we understand how challenging gMG can be and how transformative effective infusion therapy can be for patients.

Our established reputation and commitment to staying current with the latest therapies, including innovative treatments like Vyvgart®, give patients confidence they are receiving safe, effective, and cutting-edge care from an experienced team.